Prevent · Optimize · Reverse

Enhancing Health, Extending Life.

Personalized longevity and preventive medicine — physician-led, data-driven, whole-person. We detect risk early, intervene precisely, and build the plan that adds life to your years.

● 100% telehealth-focused practice — your full plan is delivered virtually, with home-based testing kits and connected wearables. Care from anywhere we're licensed.

Physician-Led

Expert care, designed around you.

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Evidence-Based

Validated testing and proven therapies.

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Data-Driven

Real numbers. Measurable progress.

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Whole-Person

Body, mind, and lifestyle in balance.

The Core Difference

"We identify hidden cardiometabolic disease before symptoms using advanced biomarkers, imaging, and physiology testing."

Our Approach

We don't guess. We measure.

Then we build a precise plan around your biology, your movement, your recovery, and your daily habits — and we adjust it monthly with real data.

01Risk Detection Engine

Medical Core

Genetics, advanced functional labs, hormones, gut health, home-based VO₂ Max & lactate testing, DEXA, CGM, and metabolic age assessment.

02Response Tracking

Physiology Layer

PRYSM oxidative stress scan, wearable tracking (sleep, HRV, recovery, strain), and comprehensive cognitive testing.

03Functional Foundation

Movement & Posture

Posture analysis, mobility correction, ergonomic guidance, and ONMM (Osteopathic Neuromusculoskeletal Medicine) referral when clinically indicated.

04Sustain & Optimize

Recovery & Adherence

Red light therapy, coaching, training support, lifestyle optimization, and HBOT referral when indicated.

Your 6-Month Journey

From baseline to performance.

Six structured phases — built around your biology, refined with continuous data.

1Weeks 0–2

Baseline

Run every assessment and establish your full baseline picture.

2Weeks 2–4

Integration

Build your risk map. Identify 3–4 priority targets.

3Months 1–2

Intervention

Nutrition, exercise, posture, hormones — start the protocol.

4Months 2–4

Stabilization

Biweekly check-ins. Retest the metrics that matter.

5Months 4–5

Optimization

Refine. Reinforce. Build the daily habits that hold.

6Months 5–6

Performance

Reassess every layer. Lock in long-term maintenance.

Meet Your Physician

Dr. Karthik Yeruva, M.D.

Board-certified Internal Medicine physician focused on clinical lipidology and longevity medicine, with specialized expertise in Obesity Medicine and Hypertension. After years on the front lines of hospital medicine watching uncontrolled metabolic disease shorten lives, Dr. Yeruva built MitoGen MD to do the opposite — measure early, intervene precisely, and prevent disease before it begins.

Clinical LipidologyLongevity MedicineABOM DiplomateCertified Hypertension Specialist
How We're Different

This isn't your annual physical.

We're not replacing your primary care doctor — we're adding the precision longevity layer your PCP can't deliver in a 15-minute insurance-covered visit.

Standard PCP Care

Reactive · Episodic · Generic

  • Annual physicals — once-a-year snapshots, not trends
  • Insurance-driven testing menu — basic CBC, lipid panel, A1C
  • 15-minute visits — no time for a personalized plan
  • Reactive: catches disease after it has already developed
  • No coaching, no continuous data, no follow-through between visits
  • "Your labs look fine" — even when you don't feel fine
MitoGen MD

Proactive · Continuous · Precise

  • Continuous, longitudinal data — wearables, CGM, biweekly check-ins
  • Advanced testing your PCP can't order: VO₂ Max, lactate, ApoB, hs-CRP, DEXA, hormones, gut, cognition
  • Hour-long virtual visits — full plan built around your biology
  • Proactive: detects metabolic dysfunction years before it becomes disease
  • Daily dietitian, biweekly physician, ongoing protocol refinement
  • Every recommendation tied to a measurable change

Keep your PCP for acute illness, prescriptions, screening, and insurance-covered preventive care. Use MitoGen MD for the deep biological work that the standard system isn't built for.

What We Track

Seven core metrics. One precise plan.

VO₂ Max
Fitness & longevity indicator
Glucose Stability
Time in range · spikes · variability
Cardiometabolic Markers
ApoB · insulin · hs-CRP · lipids
Body Composition
Muscle · visceral fat · body fat %
Inflammatory Markers
hs-CRP · cytokines · oxidative stress
Hormones
Balance · energy · libido · mood · metabolism
Cognitive Function
Memory · attention · processing · executive
The End Goal

Move the numbers that matter.

Every plan in this program drives toward four measurable targets that strongly predict your next 20 years of health.

↓ Visceral Fat
The dangerous fat around your organs
↓ A1C
3-month glucose control marker
↓ ApoB
The truest cardiovascular risk number
↑ VO₂ Max
Strongest single predictor of mortality
Expected Outcomes

What 6 months together looks like.

Better energy and stamina. More capacity for the work and life you want to lead.
Improved glucose control & insulin sensitivity. Steadier energy. Lower long-term metabolic risk.
Lower inflammation and oxidative stress. Measurable, not assumed.
Improved posture, mobility & reduced pain. Better mechanics, fewer aches, more freedom of movement.
Reduced cardiometabolic risk. The numbers that predict the next 20 years.
Longer healthspan, better lifespan. The whole point.
Real Results, By Design

What this looks like in practice.

Composite scenarios built from the same phases and metrics every MitoGen MD member goes through — illustrating the kind of transformation the program is designed to produce.

Illustrative Example

The Executive with "Normal" Labs

Male, 40s — annual physical said everything was fine, but afternoons felt like a wall.

Baseline testing uncovered elevated ApoB and hs-CRP — invisible on a standard lipid panel — plus visceral fat above the healthy range. VO₂ Max and lactate testing pinpointed his zone 2 threshold, and a personalized exercise prescription built around it retrained his aerobic base. Six months of precision intervention later, the numbers moved and so did his energy.

ApoB ↓Visceral Fat ↓VO₂ Max ↑Zone 2 Identified
Illustrative Example

The Prediabetes Reversal

Female, 50s — A1C in the prediabetic range after months of generic diet advice that went nowhere.

Continuous glucose monitoring revealed exactly which foods were driving her spikes. Functional labs also turned up low omega-3 levels and a genetic predisposition to sluggish liver detoxification pathways. A combined diet, exercise, and targeted supplement prescription was initiated — and by her 4-month recheck, her A1C had returned to normal range and her omega-3 levels had climbed into target range.

A1C ↓Insulin Sensitivity ↑Omega-3 ↑Detox Pathway Identified
Illustrative Example

The Gut-Lipid Connection

Female, 40s — total cholesterol looked "normal," but family history of heart disease raised deeper questions.

Advanced testing found elevated ApoB and a high small dense LDL particle count — the pattern that actually drives cardiovascular risk. Genetic testing identified an APOE4 variant, reshaping her nutrition strategy around it. Gut health testing then uncovered underlying dysbiosis fueling the problem. A targeted gut restoration protocol and APOE4-informed dietary changes brought particle counts and ApoB down together.

APOE4 IdentifiedDysbiosis CorrectedSmall Dense LDL ↓ApoB ↓

These are composite, illustrative scenarios based on the program's structure and typical metric improvements — not verified individual patient outcomes. Individual results vary.

Is This For You?

Who thrives in this program.

MitoGen MD is built for people who want to act before disease shows up — not after.

Your labs come back "normal," but you don't feel like yourself.
You have a family history of heart disease, diabetes, or early cognitive decline — and want to change your trajectory.
You're managing prediabetes, insulin resistance, or stubborn weight and haven't gotten real answers.
You're an athlete or high performer who has plateaued despite consistent training.
You're navigating perimenopause or menopause and want a plan built around your changing biology.
You carry excess body fat — or you're "skinny fat," a normal weight with poor body composition underneath.
You have hypertension or live under chronic high stress that never seems to let up.
You've had a sitting job for years and don't feel energetic anymore.
You want proactive, data-driven care — not another 15-minute visit and a pat on the back.
Not sure if you're a fit? Start with a free initial consultation.

We'll talk through your goals, history, and concerns — no obligation — to see if MitoGen MD is the right next step for you.

Our Promise

Data-driven. Personalized. Physician-led. Results-focused.

We don't just add years to life.
We add life to years.

Let's build your healthiest future. One step. One habit. One metric at a time.

Book Your Consultation